# The Center for Innovation and Translation of Point of Care Technologies for Equitable Cancer Care (CITEC)

> **NIH NIH U54** · RICE UNIVERSITY · 2024 · $1,300,000

## Abstract

Abstract:
Cancer is the first or second leading cause of premature death in 134 of 183 countries, and it is estimated that global
incidence of cancer will increase by 50% from 2018 to 2040. The number of cases is projected to double in countries with
low Human Development Index; these countries have the least resources and infrastructure to adequately care for cancer
patients. Disparities exist within countries; in the US, racial and ethnic minorities and other medically underserved
populations share a disproportionate burden for many types of cancer. Most cancers can be cured if detected early and
treated effectively. To reduce premature death, the World Health Organization recommends implementing early cancer
detection and prevention programs at the primary care level. Yet, existing tests for early cancer detection are too complex
and/or expensive to implement in primary care settings, particularly in medically underserved areas. We will establish the
Center for Innovation and Translation of Point-of-Care Technologies for Equitable Cancer Care (CITEC) to identify high-
priority clinical needs for POC cancer technologies; to accelerate development of effective, affordable technologies to
meet these needs; to evaluate and improve the clinical and public health impact of POC technologies in diverse settings;
and to train developers and users to create and disseminate more equitable POC technologies. CITEC will prioritize
development of POC tests to detect cancers that arise in epithelial surfaces. Initially, we will focus on sites accessible for
early detection because this is where POC technologies can have the most immediate impact. Targeted organ sites include
the uterine cervix, gastro-intestinal tract (esophagus, stomach, colon, rectum, anus), and oral cavity; cancers in these sites
account for 26% of global cases and 29% of global cancer deaths. CITEC builds on the highly productive 15-year
collaboration between Rice University, The University of Texas MD Anderson Cancer Center, Baylor College of Medicine,
and The University of Texas Health Science Center at Houston to develop and translate novel POC technologies to improve
cancer care in both low- and high-resource settings. Joining with collaborators in Brazil at The University of Sao Paulo and
Barretos Cancer Hospital and partners in Mozambique at The Universidade Eduardo Mondlane and Ministry of Health, we
will create a collaborative center to support technology development and engage and support a global community of
investigators dedicated to creating and scaling POC technologies for equitable cancer screening and diagnosis to facilitate
early treatment. CITEC will support development of POC technologies to promote high priority topics of NIH cancer
research, including precision approaches to prevention, screening and early detection, reducing disparities in cancer
outcomes, and building a diverse workforce able to translate POC technologies from research and development to
equitable i...

## Key facts

- **NIH application ID:** 10928771
- **Project number:** 5U54EB034652-02
- **Recipient organization:** RICE UNIVERSITY
- **Principal Investigator:** Sharmila Anandasabapathy
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,300,000
- **Award type:** 5
- **Project period:** 2023-09-13 → 2028-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10928771

## Citation

> US National Institutes of Health, RePORTER application 10928771, The Center for Innovation and Translation of Point of Care Technologies for Equitable Cancer Care (CITEC) (5U54EB034652-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10928771. Licensed CC0.

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