ABSTRACT The traditional staged pipeline for moving innovations from prototype to efficacy and effectiveness testing to real‐world implementation generally results in slow dissemination and uptake of effective interventions and technologies. The CITEC Dissemination Core (DC) will work to accelerate efficient and effective translation and adoption of POC technologies for cancer screening and early detection by engaging in activities that are crucial to achieve optimal adoption and implementation. The DC will work to: 1) ensure that clinical and user needs inform device development and design; 2) proactively assess and address barriers to integrating POC technologies into real‐world health care delivery processes; and 3) train technology developers and end users to develop, evaluate, implement, and commercialize POC technologies for equitable cancer screening and diagnosis. The first aim of the DC is to collaborate with the Technical and Clinical Cores to assess, refine, formally document, and broadly communicate high‐priority unmet clinical needs associated with cancer screening and early detection that are targets for POC technologies to improve equitable cancer screening and early detection. The DC will carry out on‐site needs assessment visits at multiple global sites including medically underserved settings in the US, Brazil and Mozambique. The DC will document and publish consensus POC Technology Needs Statements each year and these will be disseminated broadly in partnership with professional societies. The second aim of the DC is to develop an implementation science roadmap for introducing POC technologies in low‐resource settings based on a case study around implementation of an existing but under‐utilized technology for cervical cancer screening. The third aim of the DC is to provide a portfolio of interdisciplinary training and educational opportunities targeted to technology developers and end‐users to accelerate the development, evaluation, implementation, and commercialization of POC technologies for equitable cancer screening and early detection. We will partner with professional societies to offer engaging, hands‐on pre‐conference workshops. Knowledge generated through these activities will inform and refine the work of other CITEC cores and POCTRN centers and will help ensure that technology prototypes supported by CITEC will have a high rate of success for market adoption, scale‐up, and implementation to address global cancer health disparities.