# Community-viable screening for ASD in 9-month-old infants using quantitative eye-tracking assays of social visual engagement > **NIH NIH R01** · EMORY UNIVERSITY · 2024 · $738,202 ## Abstract PROJECT SUMMARY This project is in response to NIMH RFA-MH-19-120 calling for the development and validation of new screening methods for autism spectrum disorder (ASD) that can be used in infancy (0-12 months of age). We will deploy a cost-effective, high-throughput methodology utilizing performance-based, objective, and highly quantitative eye- tracking assays of social visual engagement—the way in which infants visually explore, engage, and ultimately learn from and adapt to their surrounding world—collected on a standalone, mobile eye-tracking data collection device, created in our lab (the Marcus Autism Center Investigational Device, MAC-ID). We will collect eye- tracking data from a population-based sample of N=2,000 9-month-old infants recruited consecutively in primary care practices at the time of their 9-month well-child visits. These infants will be followed longitudinally from 9 until 26 months for completion of a series of sequential screening and clinical ascertainment procedures designed to maximize sensitivity and achieve clinician-best-estimate diagnostic assignments of ASD vs. non- ASD and Affected [including ASD and non-ASD developmental delays] vs. Unaffected. We will measure the accuracy of eye-tracking-based screening at the age of 9 months relative to clinician best estimate diagnosis at 24 months (primary analysis), and we will measure dimensional agreement between eye-tracking assays at 9 months relative to outcome levels of social disability, verbal ability, and nonverbal cognitive ability (secondary analyses). Our overarching goal is to develop high-quality, objective, performance-based tools that can function as an effective and community-viable means of screening for ASD and other actionable developmental delays in infancy, to ultimately facilitate improved access to and benefit from early intervention. ## Key facts - **NIH application ID:** 10929289 - **Project number:** 5R01MH121363-05 - **Recipient organization:** EMORY UNIVERSITY - **Principal Investigator:** Warren Jones - **Activity code:** R01 (R01, R21, SBIR, etc.) - **Funding institute:** NIH - **Fiscal year:** 2024 - **Award amount:** $738,202 - **Award type:** 5 - **Project period:** 2019-09-16 → 2026-02-28 ## Primary source NIH RePORTER: https://reporter.nih.gov/project-details/10929289 ## Citation > US National Institutes of Health, RePORTER application 10929289, Community-viable screening for ASD in 9-month-old infants using quantitative eye-tracking assays of social visual engagement (5R01MH121363-05). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10929289. Licensed CC0. --- *[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*