# Automated Long-Term Oxygen Therapy Control System

> **NIH NIH R44** · MINNESOTA HEALTHSOLUTIONS CORPORATION · 2024 · $1,254,816

## Abstract

Project Summary/Abstract
This proposed project relates to the development and evaluation of a novel closed-loop long-term oxygen
therapy control system that includes an innovative smartphone-based companion software application. We
hypothesize that such a system will optimize oxygen delivery in mobile patients, minimize hypoxemia and air
hunger during physical exertion, avoid hyperoxia and improve patient health-related quality of life. More than
1.5 million Americans are currently receiving long-term oxygen therapy. Drawbacks to long-term oxygen
therapy include significant limitations to patient physical activity, a heightening of social isolation and decline in
emotional well-being. Improved mobile technology is needed to address these drawbacks and improve patient
outcomes. A production prototype system will be designed, built, and evaluated.

## Key facts

- **NIH application ID:** 10929462
- **Project number:** 5R44HL160356-03
- **Recipient organization:** MINNESOTA HEALTHSOLUTIONS CORPORATION
- **Principal Investigator:** Nick Rydberg
- **Activity code:** R44 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,254,816
- **Award type:** 5
- **Project period:** 2021-09-01 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10929462

## Citation

> US National Institutes of Health, RePORTER application 10929462, Automated Long-Term Oxygen Therapy Control System (5R44HL160356-03). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10929462. Licensed CC0.

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