SUMMARY - DISSEMINATION (DIS) CORE The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern (C-THAN)'s Dissemination (Dis) Core leverages over 16 years of teaching and expertise in conducting needs assessments for Point-of-Care (POC) and home-based technologies from the Northwestern University Kellogg School of Management (Kellogg). Since 2006, our proposed Dis Core team has trained over 400 MBA students who conducted POC and home-based technology needs assessments in the following 18 countries: Botswana, Brazil, Cambodia, China, India, Kenya, Lesotho, Malawi, Mozambique, Namibia, Nigeria, South Africa, Swaziland, Tanzania, Uganda, Vietnam, Zambia, and Zimbabwe. We have conducted these needs assessments for a variety of product developers, including Northwestern University, Abbott Diagnostics, Alere, Becton Dickinson, Quidel Corporation, Minute Molecular, FIND, the Bill & Melinda Gates Foundation, and the Northwestern Global Health Foundation. During the first five years of C-THAN, we conducted needs assessments for 10 of our 26 innovators (38%), 4 (40%) with innovators from countries in Africa. These needs assessments covered a variety of conditions including HIV/AIDS, tuberculosis, hepatitis B, hepatitis C, cervical cancer, human papillomavirus, and liver cancer. On behalf of our innovators, we conducted over 120 interviews with clinicians and stakeholders defining the broader needs for diagnostics within these conditions as well as specific needs for sample collection and/or sample processing. We also obtained user feedback on innovation concepts and user steps for our innovator's sample collection innovations, POC diagnostic devices, and digital health accessories. The findings from these needs assessments not only help our innovators course correct product design and target specifications, but also allowed our broader C-THAN team to refine our annual solicitations. The C-THAN Dis Core will continue to train and/or conduct needs assessments for POC and home-based technology product developers and refine our annual solicitations based upon needs identified. The Dis Core specific aims are: 1. Facilitate and enhance interdisciplinary training on the development, evaluation, implementation, and commercialization of POC and home-based technologies for HIV/AIDS and Emerging Infectious Diseases. 2. Conduct needs assessments for POC and home-based technologies for HIV/AIDS and Emerging Infectious Diseases. 3. Disseminate the results of clinical needs and user assessment and impact analysis to relevant stakeholders.