Project Summary/Abstract – Administrative Core The Administrative Core is the organizational underpinning for the proposed studies. These are organized into five projects across four sites and four resource cores. The studies make use of an integrated approach toward the chief scientific goal of understanding the neuronal basis underlying coordinated orofacial behavior: thus the lead investigators have a wide range of expertise from genetic manipulation of viruses for brain connectivity studies and development of new tracing probes, in vivo electrophysiology to allow neuronal recording in awake behaving animals, in vivo optical imaging with adaptive optics to computer science automated image recognition routines (Projects 1 to 5). The three Resource Cores provide expertise and service for data analysis and data sharing, expertise for high precision histology and anatomy, including raw images for the shared portal of primary data in the data science core, and dissemination of adaptive optics-based two photon microscopy. The Administrative Core oversees tracking of all funding of personnel linked to projects and/or cores for these studies. Funding will be administered by a main contract to UCSD and subcontracts to Allen Institute, Ben Gurion, Boston U, Johns Hopkins, and MIT. The Administrative Core will also manager funds for our Postbaccalaureate Summer Research Program, a ten-week program is designed to help two underrepresented minorities achieve additional experience for PhD programs. The management of the budget will be the purview of a fund manager hired through UCSD Department of Physics. The scientific governance will be accomplished through regular meetings held on Zoom of an internal advisory committee that will include members from each project and resource core. Professor and Chair Jing Wang has agreed to serve as an independent ombudsman to help resolve scientific conflicts in consultation with an external scientific advisory committee, which remains to be appointed.