PROJECT ABSTRACT – LEADERSHIP AND LOGISTICS The Leadership and Logistics Core (LLC) will serve as the nexus of the Center for Coordination of Analytics, Science, Enhancement and Logistics (CASEL), coordinating and integrating the work of the other Cores as part of a larger whole and serving as the connection between CASEL, Federal partners, and the tobacco regulatory science (TRS) research community. Scientific leadership activities of this Core will capitalize on our unique central position in the TRS community to identify research priorities for the purpose of advancing the science in meaningful ways and leverage the expertise within the community to provide timely data and findings to support regulatory action. Logistical activities of the Core will be focused on communication and providing the resources, tools, and structure to support committees, Special Interest Groups (SIGs), scientific meetings, and processes for collaboration and product development. Oversight and management of CASEL activities in all Cores will emanate from the LLC, under the leadership of CASEL MPIs Ms. Jeanne Rosenthal and Dr. Robin Mermelstein. Ms. Rosenthal will have primary responsibility for managing logistical and administrative functions of the Center. Dr. Mermelstein will provide scientific guidance and direction. Ms. Miriam Galbraith will serve as Program Manager, leading CASEL's logistics team, coordinating the day-to-day activities of the Center, and serving as primary liaison to the Federal partners. Our experienced team will build on the robust infrastructure, community networks, and relationships and a record of substantial scientific and logistical accomplishments of the Center for Evaluation and Coordination of Training and Research (CECTR) and CASEL 1.0 to carry out the work of this Core for CASEL 2.0.