# Protocol Review and Monitoring System

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $289,184

## Abstract

Protocol Review and Monitoring System: Summary/Abstract
The goal of the HDFCCC Protocol Review and Monitoring System (PRMS) is to ensure rigorous scientific
review and monitoring of all clinical research undertaken in the HDFCCC. This is accomplished through a two-
stage process, first by disease-focused and discipline-focused site committees that undertake initial scientific
review of protocols, assessment of feasibility and projected accrual rates, and study prioritization; and then by
the Protocol Review and Monitoring Committee (PRMC) that reviews scientific rationale, study design,
expected accrual rates, adequacy of biostatistical input, feasibility of study completion within an appropriate
time period, and ongoing review of scientific progress, including scientific relevance and accrual rates. As part
of its review process, the PRMC undertakes prioritization of all clinical research studies across the HDFCCC.
This provides a touchpoint to assess alignment of clinical trials with the Center-wide strategic plan and
priorities, and an opportunity to prioritize research related to the cancer burden in the catchment area, high
priority cancers, and underserved or marginalized communities.

## Key facts

- **NIH application ID:** 10932226
- **Project number:** 5P30CA082103-25
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** Jennifer Leigh Clarke
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $289,184
- **Award type:** 5
- **Project period:** 1999-08-05 → 2028-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10932226

## Citation

> US National Institutes of Health, RePORTER application 10932226, Protocol Review and Monitoring System (5P30CA082103-25). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10932226. Licensed CC0.

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