# "Family Diabetes Risk Reduction"

> **NIH NIH U54** · MOREHOUSE SCHOOL OF MEDICINE · 2024 · $298,720

## Abstract

Project Summary/Abstract
Family Diabetes Risk Reduction (Family D-Risk)
 An effective intervention focused on parents and children, designed in collaboration with the
community, may decrease morbidity and mortality associated with Type 2 Diabetes (T2D) among
African Americans (AA). The goal of this project is to utilize a community-engaged research (CER)
approach to reduce T2D risk among AA families through the cultural tailoring of the Diabetes Prevention
Program (DPP). Our long-term goal is to adapt and implement a sustainable, multilevel,
evidence-based program for families at higher risk for T2D. We hypothesize that implementing a
culturally appropriate, family-oriented adaptation of the DPP, Family D-Risk, will result in improvements
in health indicators associated with increased risk for T2D among AA parents and their children. We
seek to achieve the following aims: AIM 1: Utilize a CER approach to culturally tailor a DPP-based
intervention for AA adults at high T2D risk and their children living in low resource rural areas in Albany,
GA. We will conduct focus groups and in-depth interviews with community stakeholders and families to
tailor the Family D-Risk intervention to prioritize both adults and children and better fit the needs of the
AA community in Albany, GA. AIM 2: Evaluate the efficacy of the CER-adapted Family D-Risk
intervention to improve weight, an important T2D risk factor, in AA parents with prediabetes (primary
outcome) and cardiometabolic risk factors in parents and children (secondary outcome) who participate
in the family intervention arm. We propose to implement a two-arm, randomized controlled trial with 140
families to compare: 1) family intervention (family arm) and 2) wait-list control (control arm). AIM 3:
Assess sustainability of the Family D-Risk intervention through evaluation of the local determinants of
mid- and long-term engagement, acceptability, uptake, fidelity, and compliance through measurement
of components critical to program sustainability (i.e., community engagement, acceptability, and
community input on how to sustain the program). If successful, the proposed study will provide
evidence for the utility of using a CER approach to implement a culturally tailored, family-oriented
adaptation of the DPP that will have positive effects on risk factors associated with T2D morbidity and
mortality among AA families in low resource rural communities.

## Key facts

- **NIH application ID:** 10932314
- **Project number:** 5U54MD007602-37
- **Recipient organization:** MOREHOUSE SCHOOL OF MEDICINE
- **Principal Investigator:** Rakale Collins Quarells
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $298,720
- **Award type:** 5
- **Project period:** 1997-07-07 → 2028-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10932314

## Citation

> US National Institutes of Health, RePORTER application 10932314, "Family Diabetes Risk Reduction" (5U54MD007602-37). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10932314. Licensed CC0.

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