ABSTRACT: CORE A (ADMIN) The Administrative Core proposes to provide centralized administrative management and strategic oversight of integration of the OPC-SURVIVOR Program. The administrative scope of work of Core A includes: • budget oversight and administration, • monitoring and reporting of Program, Project, and Core milestones, • NCI communications, • clerical and materials management for the Program, • centralized file management for the Program, • organization and communications with Scientific Advisory Board (SAB) including an External Advisory Committee (EAC) and engaged Patient Research Partners, • planning, organization and documentation of Program meetings and all investigators annual retreat, and • communications hub for the investigators. Aside from Program administration, Core A serves the critical role of overseeing scientific quality and integration of the Program. Drs. Hutcheson, Lai, and Fuller, as MPI of the OPC-SURVIVOR Program, in consultation with the SAB, Project Leads, and Core Leads will be responsible for providing overall direction to the integration, quality, scientific progress, and operations of the Program. Through iterative review of Projects and Core resource groups bi-annually administered in Core A, the MPIs will promote integration, stewardship, and help to prioritize resources and scientific agendas. Core A will provide investigators clear lines of scientific and administrative communication, aid in resource allocation to optimize integration and progression of the proposed Projects and facilitate resolution of problems and barriers that affect the overall Program’s progress.