# Enhanced Echinobase: A Community Genomics Research Resource For The Future

> **NIH NIH P41** · CARNEGIE-MELLON UNIVERSITY · 2024 · $193,892

## Abstract

SUMMARY OF OVERALL COMPONENT
Enhanced Echinobase: A Community Genomics Research Resource for the Future
Echinobase (Echinobase.org) is the central repository and web-accessible resource for all of the diverse
genomic data types produced by biologists working with echinoderms. Echinobase was cloned from Xenbase
to enhance database functionality, web application capabilities, and performance, all at a fraction of the cost of
doing this independently. A key added feature developed through this work are database modules that support
curation and searches of gene expression data. The look and feel of Echinobase is unique, and is tailored to its
user base including the creation of a multi-species viewer. The website provides rapid integrated capabilities
for search, view and download of a range of datatypes to empower their own research. Echinoderms are one
of only three major phyla within the deuterostomes, and therefore the species within this clade encompass a
large taxonomic diversity of body plans. Species of echinoderms are powerful model systems for
understanding the processes by which the genome controls development. The strengths of this experimental
model will continue to make it a preeminent system for the analysis of the genomic control of embryogenesis
and for analyses of developmental gene regulatory networks (GRNs) to reveal the mechanistic links between
the genome and development and consequently the genomic basis of congenital diseases.

## Key facts

- **NIH application ID:** 10933419
- **Project number:** 5P41HD095831-07
- **Recipient organization:** CARNEGIE-MELLON UNIVERSITY
- **Principal Investigator:** CHARLES A. ETTENSOHN
- **Activity code:** P41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $193,892
- **Award type:** 5
- **Project period:** 2023-09-22 → 2024-10-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10933419

## Citation

> US National Institutes of Health, RePORTER application 10933419, Enhanced Echinobase: A Community Genomics Research Resource For The Future (5P41HD095831-07). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10933419. Licensed CC0.

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