# Pathology and Bioinformatics Core

> **NIH NIH P01** · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $537,572

## Abstract

Project Summary 
The goals of the Pathology and Bioinformatics Core are to act as the primary resource for 
biomaterials, histopathology expertise, tissue biomarker development, and bioinformatics support 
for the Program. This will provide Project Investigators with the necessary expertise and 
infrastructure to support the proposed individual projects and facilitate inter-project integration. 
The work of the Core will ensure quality control, biobanking, statistical analyses, expert opinion 
for study design, availability of equipment and resources to execute experimental approaches, 
and integration of data across different datasets and species for the individual Projects. 
The specific Aims of this Core are: 1) To provide acquisition, biobanking, clinical annotation, and 
histopathologic interpretative services for human and animal tissue samples. 2) To deploy existing 
and to develop novel tissue-based biomarker assays. 3) To provide bioinformatic support and 
interpretation of genomic and transcriptomic data. 4) To develop and provide methods for 
quantitative spatial analysis of multiplexed tissue biomarker data. 
Rigorous computational tools, analysis, and expertise will provide necessary resources to each 
individual Project in the Program, and overall integration of these data will develop a 
comprehensive, integrated model of local molecular and cellular tumor-immune signaling 
networks governing immune response and escape in melanoma.

## Key facts

- **NIH application ID:** 10933668
- **Project number:** 2P01CA163222-11
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **Principal Investigator:** DAVID R LIU
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $537,572
- **Award type:** 2
- **Project period:** 2013-03-12 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10933668

## Citation

> US National Institutes of Health, RePORTER application 10933668, Pathology and Bioinformatics Core (2P01CA163222-11). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10933668. Licensed CC0.

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