# Core A: Biospecimen Processing

> **NIH NIH P50** · WASHINGTON UNIVERSITY · 2024 · $219,442

## Abstract

The goal of the Biospecimen Processing Core (BPC, Core A) is to provide high-quality, clinically annotated
biospecimens to all four research projects proposed in this SPORE application as well as ongoing and future
SPORE-sponsored DRP (Developmental Research Program) and CEP (Career Enhancement Program)
projects, and to serve as a critical biospecimen resource to the broader leukemia research community. The BPC
will be responsible for identifying and enrolling every patient referred to the Siteman Cancer Center (SCC) with
newly diagnosed hematologic malignancy (excluding multiple myeloma). Biospecimens from these patients will
be collected at multiple timepoints, processed, and stored by leveraging the extensive infrastructure of the
Siteman Cancer Center Tissue Procurement Core (TPC), a CAP-accredited biorepository with over 20 years of
experience in biospecimen banking. Clinical data will be collected prospectively by integrating with and
extending the mission of an existing Clinical Database Core (CDC), previously established as part of a Genomics
of AML (GAML) Program Project Grant (PPG) to serve as a platform for the investigation of genetic mutations
associated with the pathogenesis of MDS and AML. As such, Core A will expand upon existing SCC resources
with focused expertise and effort to comprehensively collect, annotate, quality review, and distribute
biospecimens specifically for translational leukemia and leukemia-related cancer research.

## Key facts

- **NIH application ID:** 10934210
- **Project number:** 2P50CA171963-11A1
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** MEAGAN JACOBY
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $219,442
- **Award type:** 2
- **Project period:** 2013-09-03 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10934210

## Citation

> US National Institutes of Health, RePORTER application 10934210, Core A: Biospecimen Processing (2P50CA171963-11A1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10934210. Licensed CC0.

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