# Project 1 - HEARTSPOT: Evaluating a Machine Learning System to Aid Decision-Making in the Emergency Department for Patients with ADRD

> **NIH NIH P01** · NATIONAL BUREAU OF ECONOMIC RESEARCH · 2024 · $280,729

## Abstract

OTHER PROJECT INFORMATION – Project Summary/Abstract
Project 1: HEARTSPOT: Evaluating a Machine Learning System to Aid Decision-Making in the
Emergency Department for Patients with ADRD
The HEARTSPOT project seeks to improve accuracy in the treatment of acute coronary syndrome (ACS) for
patients with Alzheimer’s disease and related dementias (ADRD). An augmented intelligence algorithm will be
deployed across a large health system’s electronic medical record through a randomized evaluation to learn
about ACS, detect risk signals for individual patients, and generate a new decision aid for emergency department
clinicians. The goal is to give clinicians as much synthesized information on patient risk as possible at the point
of deciding on the ACS treatment path. This project may improve ACS decisions for patients overall, for elderly
patients given the complexity of their care decisions, but in particular for ADRD patients, for whom the algorithm
may help fill critical information gaps necessary for clinicians to accurately assess ACS risk. While focused on
improving healthcare decision-making in emergency departments and relating to ACS treatment for patients with
ADRD specifically, Project 1 complements the work of the other four projects that all study different influences
on healthcare for ADRD patients and healthcare disparities in different settings and contexts.

## Key facts

- **NIH application ID:** 10934398
- **Project number:** 2P01AG005842-35A1
- **Recipient organization:** NATIONAL BUREAU OF ECONOMIC RESEARCH
- **Principal Investigator:** Katherine Baicker
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $280,729
- **Award type:** 2
- **Project period:** 1997-02-01 → 2029-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10934398

## Citation

> US National Institutes of Health, RePORTER application 10934398, Project 1 - HEARTSPOT: Evaluating a Machine Learning System to Aid Decision-Making in the Emergency Department for Patients with ADRD (2P01AG005842-35A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10934398. Licensed CC0.

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