# D

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2024 · $139,958

## Abstract

Project Summary (Core D: Pilot Project Core)
 The purpose of the Pilot Project Core is to fund pilot projects that are likely to produce new
collaborations, publications, and grants. We will consider the project and the applicant and will seek to fund all
career stages, genders, under-represented minorities, people with disabilities and people from disadvantaged
backgrounds. Pilot projects will not be used to supplement or prolong ongoing research, nor will they serve as
bridge funds for the maintenance of ongoing research.
 While this P30 application is a new grant, we hope to build on our experience from our previously
funded P50 center, which also had a pilot project core. The Pilot Project Core will offer 1- and 2-year grants
that will include money (up to $25,000 per year), heterogeneous stock (HS) rats, RATTACA rats (RAT Trait
Ascertainment using Common Alleles), which are HS rats selected based on genetically predicted phenotypes
as described in Core B, genotyping or analysis services or any combination thereof. We anticipate various
types of grants, for example: 1) projects to follow-up on studies that target specific genes identified by
genome-wide association studies (GWAS), for example by using mutant rats, viral vectors, or pharmacological
agents, 2) projects to collect preliminary phenotype data using HS rats, 3) project that develop new statistical,
bioinformatic or machine learning methodologies that can be used to better analyze data that have already
been generated by our center, 4) projects that use the genotyping or analysis services provided by Core C,
and 5) we will also consider awards that use complementary approaches provided that they are related to the
center’s work. For example, our P50 funded a project that examined genes identified in HS rats using a mutant
c. elegans screen. In all cases, the goal of these grants will be to strategically enhance the impact of the center
and to engage the broader scientific community. Grants will allow initiation of activities that, if successful, will
become self-sustaining.
 We describe how pilot project applications will be solicited, evaluated, and how we will use those
evaluations, in conjunction with other programmatic considerations, to make funding decisions. We also
present examples of grants that we might fund in year 1, and we describe how we will ensure that all pilot
projects will comply with all applicable federal regulations.

## Key facts

- **NIH application ID:** 10935614
- **Project number:** 1P30DA060810-01
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** Oksana O Polesskaya
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $139,958
- **Award type:** 1
- **Project period:** 2024-09-01 → 2029-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10935614

## Citation

> US National Institutes of Health, RePORTER application 10935614, D (1P30DA060810-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10935614. Licensed CC0.

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