PROJECT SUMMARY: COMPUTATION & DATA MANAGEMENT SERVICE MODULE The Vanderbilt Vision Research Center (VVRC) includes faculty investigators with strong interest in high- level imaging of visual cognition in humans, multi-electrode array neurophysiology, large-scale human bioinformatic datasets, visual behavior in awake-behaving non-human primates, and computational modeling of human and non-human primate vision. These clinical, cognitive- and systems-level investigations require expertise in computer systems administration, data collection and management, analysis, and storage, and web-based applications for experimentation. As well, other VVRC investigators require access to hardware and software maintenance and specialty programming, including web-based content and interfacing with specialty equipment made in our instrumentation service module. The purpose of the VVRC Computation & Data Management Service Module is to provide a comprehensive service for computer hardware and software that support the wide range of empirical studies our investigators conduct. The Computation & Data Management Module provides computer technology support for research needed to solve more complex challenges that face computer-dependent laboratory science. This module is a VVRC-intrinsic core and is not part of a VUMC institutional facility; therefore, the service is provided to VVRC members by request and not through the VUMC Office of Research scholarship platform. In the current funding period, the computation module directly supported 213 publications involving 23 VVRC faculty authors, including 8 of 16 current NEI R01 holders, excluding website maintenance. These are indicated as such in our Progress Report: Core Vision Publications by Investigator document. A survey of researcher plans indicates that the use of this service will increase, with moderate to extensive use by 24 of 52 VVRC faculty, including 11 of 16 current NEI R01 holders. The module, housed in approximately 500 sq ft of office, server, and storage space in Wilson Hall proximal to VVRC investigators is directed by VVRC Investigator Frank Tong, PhD (NEI R01). Using this space and personnel supported by this Core mechanism, the VVRC Computation & Data Management Module will: (1) provide hardware and software support of VVRC investigations, (2) provide data pipeline, archiving, and storage solutions, (3) provide custom programming solutions, and (4) facilitate web-based content and interfacing. These services and resources will enhance the scope of experimentation NEI-funded VVRC investigators conduct, promote innovation through the provision of custom hardware and software resources, and enhance collaboration by providing computation and data management support to those who otherwise would not have such capabilities, including early-career vision scientists, clinician-scientists competing for extramural funding for their laboratories, and VVRC investigators without access to computer expertise beyo...