# Center for Biomolecular Structure (CBMS)

> **NIH NIH P30** · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · 2024 · $4,592,873

## Abstract

Abstract - Overall Core
Brookhaven National Laboratory (BNL) has
developed a world-leading suite of experimental
facilities for the life-science research community.
Much of it is organized in the Center for
Biomolecular Structure (CBMS), which has a focus
on macromolecular crystallography (MX) and x-ray
scattering. We propose the addition of x-ray
footprinting (XFP), as a mature complementary
technique, to the resources available within CBMS.
We exploit the unprecedentedly small, bright, and
well-collimated x-ray beams of National Synchrotron
Light Source II (NSLS-II) with experimental stations
that provide the best possible crystal-diffraction and
x-ray scattering data with high levels of automation.
Our responsibility to the users is to enable
hypothesis-driven research by having sufficient
throughput to support high-volume systematic
studies, and with the capability, through our Figure 1: An integrated suite of biophysical techniques
assembly of diverse beamlines, to support multi- working together to enable world class science.
disciplinary work for complex investigations.
We will make these remarkable instruments available to the widest possible community to encourage a
passionate, diverse user community enabling their success and ours.

## Key facts

- **NIH application ID:** 10946988
- **Project number:** 2P30GM133893-06
- **Recipient organization:** BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB
- **Principal Investigator:** Sean McSweeney
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $4,592,873
- **Award type:** 2
- **Project period:** 2019-09-01 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10946988

## Citation

> US National Institutes of Health, RePORTER application 10946988, Center for Biomolecular Structure (CBMS) (2P30GM133893-06). Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/grant/nih/10946988. Licensed CC0.

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