# Assess and Design a Multi-level Intervention with Middle to Older Age Mexican Immigrants to Increase Cervical Cancer Screening in Community Health Clinics

> **NIH NIH K01** · OREGON HEALTH & SCIENCE UNIVERSITY · 2024 · $176,534

## Abstract

PROJECT SUMMARY / ABSTRACT
Cervical cancer is the fourth most common cancer affecting people with a cervix worldwide, after breast,
colorectal, and lung cancers, with 569,847 new cases every year. In the United States, cervical cancer incidence
and mortality are 7.7 and 2.3 per 100,000 women, respectively, with substantial disparities in both cervical cancer
incidence and mortality across racial and ethnic groups. Latinas, in particular, are disproportionately burdened
with cervical cancer compared to non-Hispanic Whites (NHW), with incidence and mortality rates 50% higher
than NHWs. Among women diagnosed with invasive cervical cancer, Latinas are more likely than NHWs to be
diagnosed at an advanced stage, when there are fewer treatment options. Despite the average age of diagnosis
of all cervical cancers occurring around age 50, the majority of screening interventions focus on younger and/or
reproductive aged people with a cervix. Thus, there is growing urgency for improving cervical cancer prevention
among middle to older age women nationally and internationally. In the U.S., middle to older age immigrant
Latinas are disproportionately likely to be served at settings like Community Health Centers (CHCs). In 2017,
56% of poor and foreign-born Latina/os lived within two miles of a CHC. CHCs provide critical infrastructure and
offer healthcare to historically underserved populations (e.g., those without insurance). Evidence also suggests
that there are fewer racial/ethnic healthcare disparities among patients served by CHCs, underscoring the
importance of studying and understanding the care delivered in these settings. Therefore, the goals of the
proposed research, as part of a career development award, are to (1) describe cervical cancer screening rates
in a 23-state network of CHCs from 2012 to 2023 among middle to older age Mexican immigrants; (2) examine
individual, organizational, and structural level facilitators and barriers to cervical cancer screening among middle
to older age Mexican immigrants in three CHCs located in the Pacific northwest; and (3) co-develop a multi-level
intervention to improve cervical cancer screening among middle to older age Mexican immigrants in CHCs. This
career development award will establish Dr. Vasquez Guzman as a multi-disciplinary investigator focused on
implementing and disseminating novel primary care multi-level interventions that target complex, underserved
patient populations to reduce disparities in ongoing and regular timely and high-quality cervical cancer prevention
and screening services in safety-net settings. The K01 award provides mentored training for Dr. Vasquez
Guzman to develop expertise in 4 areas: (1) team science and the integration of social science and clinical
research approaches; (2) skills and knowledge in both intervention and implementation science (3) cervical
cancer screening and cancer communication skills; and (4) expand community engaged expertise. To achieve
these goals, Dr...

## Key facts

- **NIH application ID:** 10947341
- **Project number:** 1K01CA292141-01
- **Recipient organization:** OREGON HEALTH & SCIENCE UNIVERSITY
- **Principal Investigator:** Cirila Estela Vasquez Guzman
- **Activity code:** K01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $176,534
- **Award type:** 1
- **Project period:** 2024-08-01 → 2029-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10947341

## Citation

> US National Institutes of Health, RePORTER application 10947341, Assess and Design a Multi-level Intervention with Middle to Older Age Mexican Immigrants to Increase Cervical Cancer Screening in Community Health Clinics (1K01CA292141-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10947341. Licensed CC0.

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