# Digital Screening and Brief Intervention for Perinatal Substance Use in Home Visiting

> **NIH NIH R34** · PARTNERSHIP TO END ADDICTION · 2024 · $254,017

## Abstract

Abstract
The early postpartum period is a time of significant risk for escalating substance use (SU), as many people who
reduce their SU during pregnancy return to pre-pregnancy levels within 3 months postpartum. Addressing
postpartum SU is key to preventing negative maternal and child health outcomes, but postpartum mothers are
unlikely to seek treatment for SU, due to stigma and fear of child removal. Home visiting (HV), a nationally
available voluntary supportive intervention for high-risk families during the perinatal period, is a promising venue
for reaching new mothers to prevent SU, as it is often one of the only service touchpoints for vulnerable families
during the postpartum period. However, most widely used HV models do not have standardized protocols for
identifying and addressing SU risk. Our team adapted an electronic screening and brief intervention (e-SBI) for
SU and tailored it to the HV context (SBI-HV). The SBI-HV included an e-SBI completed by HV clients
confidentially in between home visits, and a home visitor facilitation component to support integration of the e-
SBI into routine HV. A prior study demonstrated preliminary feasibility and acceptability of SBI-HV. The proposed
study aims to further optimize the SBI-HV by applying a factorial design to examine preliminary impacts of three
SBI delivery strategies: a single e-SBI session (main e-SBI), the main e-SBI plus a booster session (booster e-
SBI), and 4 weeks of tailored text messaging following e-SBI. Additionally, we will systematically assess
implementation facilitators and barriers to inform development of targeted implementation strategies to support
sustainable integration of SBI-HV into routine HV. The proposed R34 will use a Type 1 hybrid implementation-
effectiveness design with a pilot 3X2 factorial trial and apply the RE-AIM and PRISM implementation frameworks
to achieve the following specific aims: (1) test the impact of 3 SBI-HV delivery strategies (main e-SBI; main e-
SBI + booster; text messaging) on postpartum SU, maternal self-efficacy, motivation to avoid SU, and HV
retention; (2) evaluate feasibility, acceptability, fidelity, and facilitators and barriers to the SBI-HV delivery
strategies; and (3) develop tailored implementation strategies to support SBI-HV integration into routine HV. We
will partner with the Kansas Healthy Families (HF) multi-site HV system to complete study aims in 3 phases. The
pre-implementation phase will include a mixed-methods assessment of PRISM domains aimed at selecting
implementation program sites, promoting buy-in from key staff, and informing local adaptations to the SBI-HV.
The implementation phase will include a pilot 3X2 factorial trial with 120 clients and 20 home visitors at 5 sites
to obtain proof-of-concept data on the individual and combined impacts of the SBI-HV delivery strategies. The
post-implementation phase will include qualitative interviews with factorial trial participants and HV staff to assess
implemen...

## Key facts

- **NIH application ID:** 10948653
- **Project number:** 1R34DA061238-01
- **Recipient organization:** PARTNERSHIP TO END ADDICTION
- **Principal Investigator:** SARAH E. DAUBER
- **Activity code:** R34 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $254,017
- **Award type:** 1
- **Project period:** 2024-06-15 → 2027-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10948653

## Citation

> US National Institutes of Health, RePORTER application 10948653, Digital Screening and Brief Intervention for Perinatal Substance Use in Home Visiting (1R34DA061238-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10948653. Licensed CC0.

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