# Development of Cortical Bone Mechanics Technology for Enhancing the Diagnosis of Osteoporosis

> **NIH NIH R44** · OSTEODX INC. · 2024 · $50,000

## Abstract

PROJECT SUMMARY
This administrative supplement will fund development of regulatory plans in support of the commercialization of
OsteoDx’s Cortical Bone Mechanics Technology (CBMT) that is being developed and validated by parent grant
NIA R44AG058312. The parent grant is developing and validating the clinical utility of our novel osteoporosis
related diagnostic device that non-invasively measures the mechanical properties of cortical bone and provides
direct information about bone strength and quality that is not accessible by other diagnostic modalities. The
primary scope of work of the parent grant are studies that demonstrates the accuracy (aim 1) and clinical
precision (aim 2) of the final design production version of the medical device, and advances safety and regulatory
compliance (aim 3). The company’s Phase IIB grant award did not include specific funding and aims for several
pressing product development needs that ultimately would help OsteoDx making better technical decisions,
minimizing technical risks, and facilitate the developing and commercialization of our CBMT product (e.g.,
intellectual property protections). As such, we are requesting this supplemental funding via the SBIR Technical
and Business Assistance (TABA) program. Specifically, OsteoDX is submitting this request to provide support
for 1) intellectual property protections, 2) market research and validation, and 3) assistance with product sales.

## Key facts

- **NIH application ID:** 10948972
- **Project number:** 3R44AG058312-04S1
- **Recipient organization:** OSTEODX INC.
- **Principal Investigator:** Brian C Clark
- **Activity code:** R44 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $50,000
- **Award type:** 3
- **Project period:** 2017-12-01 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10948972

## Citation

> US National Institutes of Health, RePORTER application 10948972, Development of Cortical Bone Mechanics Technology for Enhancing the Diagnosis of Osteoporosis (3R44AG058312-04S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10948972. Licensed CC0.

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