Modified Project Summary/Abstract Section The Administrative Core will oversee all planning activities involved in establishing the infrastructure and research partnerships needed to support the Center’s future research and thus ensure that the Community Catalyst (ImpaCts of extreme heAT and Air quaLitY reSearch cenTer) Center’s goals are achieved. Led by a transdisciplinary team with substantial experience in large clinical research networks with similar infrastructure and administrative needs, the Administrative Core will conduct the following tasks. (1) Oversee and support all planning process operations by serving as the coordination hub for all Center efforts, including: strategic planning for the Center’s sustainment post-planning period; managing budget and resources; meeting regulatory, reporting, and human subjects protection requirements; tracking and coordinating all Cores’ activities; collaborating with the national Center network and funding agency; and coordinating the External Advisory Board. (2) Direct all Center capacity building and sustainment planning activities, including: creating the Center’s highly innovative data infrastructure by linking EHR data from OCHIN’s national network of primary care community health centers (CHCs) and the Confluence Project’s granular data on extreme heat and poor air quality events, yielding a nationally unique data resource that will be available to collaborators; supporting the creation of a transdisciplinary Learning Community of scientific and community partners that generate a research agenda aimed at mitigating extreme heat and poor air quality event-induced health impacts in CHC populations; developing at least two large research funding proposals designed to meet identified research needs; supporting two early-stage investigators’ development; and creating a health informatics tool that integrates real-time data on extreme heat and poor air quality events (heat spikes, poor air quality) into the EHR shared by OCHIN’s CHCs, to support future interventions using these data. (3) Widely disseminate and translate findings both within and beyond the Center’s Learning Community to inform the action-oriented spread of new knowledge to varied stakeholders and target audiences. (4) Rigorously evaluate the progress of the Center planning process in meeting its goals and objectives, regularly update Center leaders and funders on evaluation findings, and adapt processes as necessary. By completing these tasks, the Administrative Core will optimize the Center’s ability to generate a much-needed long-term body of research on the mitigation of extreme heat and poor air quality event-induced health impacts in the rural / low-income U.S. populations served by primary care CHCs.