# Cost and Non-Cost Barriers to Use of Novel AD Therapeutics among Older Hispanic or Latino Adults

> **NIH NIH R61** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $311,341

## Abstract

Project Summary
The goal of this project is to assess the role of cost-associated barriers to new and future novel
AD/ADRD therapeutics in Hispanic or Latino older adults. Our work in the first (planning) phase
of the project will include semi-structured interviews with a cohort of Latino adults created as
part of the team’s ongoing work on diversity in clinical trials and an existing group of Latino
patients with AD/ADRD and their caregivers. The interviews will inform a subsequent
population-based survey to be fielded in the Understanding America Study, an online panel
study housed at the University of Southern California. Both the interviews and the survey will
elucidate cost and non-cost barriers to the use of new novel dementia therapeutics. The survey
will more fully and systematically capture the contribution of environmental, sociocultural,
behavioral, and biological factors to the demand for and use of these new medications for older
Hispanic adults and relative to non-Hispanic adults. The second, implementation stage of our
work will analyze existing Medicare claims and Encounter data to understand real world use
patterns. We will then use the team’s well-established dynamic microsimulation to estimate the
downstream impacts of use on cognitive and physical health, costs, and quality of life of older
Hispanic or Latino adults with dementia. The dynamic microsimulation model will be informed by
the work conducted in all other parts of the project both in terms of parameter inputs and
simulated scenarios.

## Key facts

- **NIH application ID:** 10977612
- **Project number:** 1R61AG089049-01
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Mireille Jacobson
- **Activity code:** R61 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $311,341
- **Award type:** 1
- **Project period:** 2024-09-15 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10977612

## Citation

> US National Institutes of Health, RePORTER application 10977612, Cost and Non-Cost Barriers to Use of Novel AD Therapeutics among Older Hispanic or Latino Adults (1R61AG089049-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10977612. Licensed CC0.

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