# Network on Life Course Health Dynamics and Disparities in 21st Century America Renewal

> **NIH NIH R24** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $443,785

## Abstract

Project Summary/Abstract
Most measures of adult health and longevity in the United States lag well behind those of other wealthy countries.
Despite widening recognition of this crisis, we have only a limited understanding of its causes and few strategies
to reverse them. This proposal, a renewal of the highly successful Network on Life Course Health Dynamics and
Disparities in 21st Century America (NLCHDD) funded for the past ten years by the National Institute on Aging,
lays out a plan to further develop the scientific groundwork, human capital, and data and analytic infrastructure
to answer critical questions about the U.S. health and longevity crisis. Our overarching objective over the next
five years is to strengthen and focus the NLCHDD to generate new evidence and disseminate data and analytic
resources to better understand the trends and disparities in U.S. adult health and longevity across the life course
and social and geographic contexts. We will do so through four specific aims. First, we will direct attention and
resources toward five targeted scientific questions that will shed light on the multi-layered determinants of the
troubling trends and growing disparities in U.S. adult health and longevity. These questions (described in detail
in the proposal) focus on how social and geographic contexts—separately and collectively—shape trends and
disparities in adult health and longevity across the life course. Second, we will strategically expand the
interdisciplinary Network of emerging, established, and underrepresented scientists who will collaborate to
investigate the key scientific questions. Third, we will provide development and training opportunities for Network
scientists via pilot grants, grant proposal mentoring, working groups, and annual meetings. Fourth, we will
develop and disseminate data and analytic resources to foster innovative research on the key scientific questions
and advance science in this critical area. Our Network is innovative in its focus on the multi-layered contextual
determinants of trends and disparities in adult health and longevity across the life course; in its openness and
evolving nature; in its efforts to incorporate emerging investigators with more established ones; and in its central
concern for support, mentoring, and development of emerging and underrepresented scholars. This emphasis
on human capital development is reflected in all aspects of the Network's organization and operation. Our
Network is also unique in its attention to focusing on research that can inform policies and interventions and
provide the foundation for future research advances. Finally, our Network is unique in that it will facilitate the
expansion, integration, and public dissemination of new and existing data resources for population health
determinants across social and geographic contexts. The renewal Network brings together a PI team and four
sites that span the U.S. with substantial experience in developing large-scale...

## Key facts

- **NIH application ID:** 10978133
- **Project number:** 2R24AG045061-11
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** JENNIFER A AILSHIRE
- **Activity code:** R24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $443,785
- **Award type:** 2
- **Project period:** 2014-09-15 → 2029-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10978133

## Citation

> US National Institutes of Health, RePORTER application 10978133, Network on Life Course Health Dynamics and Disparities in 21st Century America Renewal (2R24AG045061-11). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10978133. Licensed CC0.

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