# CLINTRUSC Health Research Core (HR)

> **NIH NIH P20** · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · 2024 · $552,437

## Abstract

PROJECT SUMMARY
The Health Research (HR) Core of the Center for Clinical & Translational Research at the University of South
Carolina (CLINTRUSC) serves as the hub for the Pilot and Developmental (P&D) Project Program. HR Core
support of P&D projects is critical for 1) growth of CLINTRUSC’s clinical research workforce and 2) advancing
clinical and translational (C&T) research that serves the needs of the communities in the Midlands of South
Carolina (SC). In concert with the Studies Review & Support Unit (SRSU) of the Administrative Core (AC), the
HR Core will oversee every aspect of the P&D program from solicitation of P&D project proposals to
dissemination of study findings that result from P&D projects. The HR Core will be led by two senior investigators
(Drs. Bonilha and Murphy) with strong records of attaining extramural funding in complementary research areas
(clinical and pre-clinical, respectively). As Leaders of the HR Core, they will work together to bridge the
translational gap between basic and clinical research. A Project Manager and a Compliance Manager,
responsible for the day-to-day operations of the HR Core, complete the HR Core team. The overall goal is to
establish a robust C&T science program with a focus on diseases that affect populations in the Midlands of SC.
To achieve this goal, the HR proposes three specific aims: 1) encourage collaboration between investigators
across different disciplines and at different career levels; 2) provide funds for P&D projects for CLINTRUSC
investigators to generate preliminary data for extramural applications; 3) develop procedures for ongoing
oversight of the P&D project program. The HR Core will work closely with the AC, the Professional Development
(PD) Core, the Community Engagement and Outreach (CEO) Core, and the Research Design, Compliance, and
Data Management (RDCD) Core to ensure that CLINTRUSC investigators have the support and infrastructure
needed to successfully complete their P&D projects. The AC is the management and governance entity of the
CLINTRUSC overseeing all operations. The PD core provides an intensive mentoring program to ensure that
P&D awardees receive support in mentoring and grant writing so that their P&D projects are transformed into
successful extramural awards. The RDCD provides guidance in study design, statistics, and data management
as well as compliance. The CEO will facilitate recruitment and retention, notably including special populations.
Interactions between CLINTRUSC Cores will ensure that every P&D awardee receives all necessary support to
ensure the success of their projects. The HR Core has established metrics to define success and evaluation of
these metrics and the HR Core at large will be assessed annually by CLINTRUSC Directors, the Cores Review
and Support Unit, and the External Advisory Committee. The goal of the HR Core is to permit the emergence of
a cadre of strong, diverse, adequately mentored and comprehensively supported translationa...

## Key facts

- **NIH application ID:** 10984242
- **Project number:** 1P20GM155896-01
- **Recipient organization:** UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
- **Principal Investigator:** Leonardo F Bonilha
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $552,437
- **Award type:** 1
- **Project period:** 2024-07-15 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10984242

## Citation

> US National Institutes of Health, RePORTER application 10984242, CLINTRUSC Health Research Core (HR) (1P20GM155896-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10984242. Licensed CC0.

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