PROJECT SUMMARY / ABSTRACT In response to PA-20-272, this supplement study proposes to evaluate the feasibility and acceptability of a linguistically adapted mobile health (mHealth) intervention (RAISE) for Spanish speaking caregivers of legally involved youth. The proposed research supports Goals 2 and 5 of the 2022-2066 NIDA Strategic Plan by bolstering family support for adolescents using substances and translating research on mindfulness-based stress reduction into an innovative mHealth application. Latinx youth are overrepresented in the juvenile legal system, making up 22% of youth in residential facilities (including residential treatment centers, detention centers, training schools, and juvenile jails and prisons).1 Although inequities in Latinx youth incarceration have improved over the past decade, they remain 28% more likely to be detained or committed in juvenile facilities compared to their white peers.2 Monolingual Spanish speaking caregivers face additional challenges navigating the juvenile legal system due to the lack of linguistically accessible resources in the community and within the juvenile court system. The RAISE app, which was developed under the Parent K23, is a parenting stress reduction intervention mHealth app that was co-designed with English speaking caregivers of legally involved youth using participatory informatics. RAISE is currently only available in English, however the co-design team included 1 bilingual (English, Spanish) Latinx caregiver and the app was tested by 6 additional users in an open trial, 25% of whom identified as Latinx. The inaccessibility of RAISE in languages other than English has been raised as a concern by our collaborating systems partners due to the high number of monolingual Spanish speaking caregivers in Northern California, where the work is primarily being conducted. Additionally, the Institutional Review Board at the University of California, San Francisco where the PI is located commented that there is not a clear scientific rationale for exclusion of caregivers based on English language proficiency, particularly given ethnoracial inequities in representation in the legal system. Latinx individuals in the U.S. are interested in using mHealth interventions3 and Latinx smartphone users are more likely than whites to use a health app4, however most studies of mHealth interventions do not include or have low rates of Latinx participation. The current supplement would allow for content translation to make the RAISE app available to Spanish speaking caregivers who could benefit and provide crucial information about the equitable and ethical use of digital health interventions with Spanish speaking caregivers of legally involved youth. The proposed research will also expand Dr. Folk's work on improving behavioral health outcomes for marginalized youth and their families by advancing the linguistic and cultural accessibility of her work. Findings will be used as the foundation for a larger...