# Innovative Network on the Science and Practice of Implementation, Research, and Engagement Center (INSPIRE)

> **NIH NIH UM2** · WASHINGTON UNIVERSITY · 2024 · $1,996,048

## Abstract

ABSTRACT
The Innovative Network on the Science and Practice of Implementation, Research, and Engagement Center
(INSPIRE) seeks to advance the science and practice of dissemination and implementation (D&I) science
research in low-to-middle income countries by adapting, scaling up, and sustaining evidence-based HIV
interventions for adolescents and young adults (AYA). The Center offers a unique opportunity to conduct this
paradigm-shifting work as part of the Prevention and Treatment through a Comprehensive Care Continuum for
HIV-affected adolescents in resource-constrained settings implementation science network (PATC3H-IN).
Using an Appreciative Inquiry lens that focuses on the strengths within a system that fuels change, our mission
is to serve as a hub for optimizing synergistic D&I research that appreciates, coordinates, and magnifies
insights on adaptation, scalability, and sustainability with communities of interest from across the network via
our Capacity Supporting Core (CSC), Advanced Methods and Modeling Core (AAMC), and Community
Engagement and Dissemination Core (CEDC). Communities of interest in the six PATC3H-IN countries
(Nigeria, Malawi, Kenya, South Africa, Zambia, Tanzania) include researchers, implementers, community
members, policymakers, and family members (especially guardians), friends, and adolescents and young
adults (AYA). Our vision aligns with global goals to end the HIV epidemic among AYA. Our specific aims are:
1) Design and deliver cutting-edge implementation science training tailored to the needs of the HIV response to
adolescents (Capacity Supporting Core); 2) Provide advanced methods and modeling expertise to combine
diverse insights from the individual PATC3H-IN Clinical Research Centers (CRCs) together (Advanced
Methods and Modeling Core); 3) Develop a shared strategy for community engagement and disseminating
insights from PATC3H-IN to key communities of interest (Community Engagement and Dissemination Core);
and 4) Evaluate INSPIRE progress and iteratively adapt, improve, and contribute to the network and science
(Administration and Evaluation Unit). By creating a centralized mechanism to harness strength, listen, and
convene across the networks, the INSPIRE Center will provide training, advanced methods, and engagement
functions that will augment the findings of each CRC individual study across the HIV prevention and treatment
care continuums, thus reducing inequities for AYA populations in LMIC settings and optimizing the translation
of research findings into real-world impact.

## Key facts

- **NIH application ID:** 10995947
- **Project number:** 1UM2HD116395-01
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** Elvin H. Geng
- **Activity code:** UM2 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,996,048
- **Award type:** 1
- **Project period:** 2024-09-13 → 2028-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10995947

## Citation

> US National Institutes of Health, RePORTER application 10995947, Innovative Network on the Science and Practice of Implementation, Research, and Engagement Center (INSPIRE) (1UM2HD116395-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10995947. Licensed CC0.

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