# A Multi-Method Investigation of the Role of Reward-Related Impulsivity in the Development of Alcohol Expectancies in Early Adolescence

> **NIH NIH F31** · UNIVERSITY OF MISSOURI-COLUMBIA · 2024 · $40,219

## Abstract

PROJECT SUMMARY/ABSTRACT
Broad/Long Term Objectives: The goals of this application are to: 1) conduct a novel test of the Acquired
Preparedness Model (APM) examining the moderating role of reward-related impulsivity on the relationship
between familial alcohol exposure and alcohol expectancies in early adolescence and 2) utilize advanced
statistics to identify latent profiles of trait, behavioral, and neural indicators of impulsivity in early adolescence.
Specific Aims: The proposed project aims to 1) identify the latent structure of a reward-related impulsivity
neuroimaging measure in early adolescence, 2) test the role of reward-related impulsivity in the proposed
developmental pathway of the APM, and 3) utilize person-centered heterogeneity analyses to identify distinct
profiles of impulsivity in early adolescence. To complete the proposed project, the applicant will receive training
in multivariate statistical methods, secondary neuroimaging analysis, and scientific writing. Training will be
obtained via 1) meetings with expert consultants, 2) coursework, and 3) conference and workshop attendance.
Method: The project will consist of secondary data analysis of the Adolescent Brain Cognitive Development
(ABCD) study dataset. Latent variable modeling will be utilized to examine the latent structure of the Monetary
Incentive Delay (MID) task in the ABCD sample and identify neural coactivation patterns associated with
developmental risk factors for AUD. Structural equation models will be used to test the APM, looking at multi-
method reward-related impulsivity variables as moderators of the relationship between familial alcohol exposure
and alcohol expectancies. Supplementary analyses will also be conducted with all available questionnaire,
behavioral, and neural indicators of impulsivity to explore distinct profiles of impulsivity in the ABCD sample.
Significance: The proposed project will advance understanding of the developmental mechanisms contributing
to risk for early alcohol use initiation, clarify the organization of heterogeneous impulsivity constructs in early
adolescence, and identify distinct neural underpinnings of reward impulsivity in early adolescence associated
with alcohol risk. The results of the project will allow for more effective tailoring of prevention and intervention
efforts for adolescent alcohol use.
Training Plan and Environment: The training plan will provide the applicant with quantitative, substantive, and
practical training to facilitate a successful career as an independent addiction scientist. The applicant will receive
training in developmental neuroscience, advanced multivariate statistics, and scientific writing. Training will take
place at the University of Missouri’s Department of Psychological Sciences, which has an outstanding addiction
training program funded by an NIAAA training grant (T32 AA013526; PI: Denis McCarthy). The mentoring team
consists of experts in developmental psychopathology (Dr. McCarthy...

## Key facts

- **NIH application ID:** 10997162
- **Project number:** 1F31AA031627-01A1
- **Recipient organization:** UNIVERSITY OF MISSOURI-COLUMBIA
- **Principal Investigator:** Anna Porter
- **Activity code:** F31 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $40,219
- **Award type:** 1
- **Project period:** 2024-09-01 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10997162

## Citation

> US National Institutes of Health, RePORTER application 10997162, A Multi-Method Investigation of the Role of Reward-Related Impulsivity in the Development of Alcohol Expectancies in Early Adolescence (1F31AA031627-01A1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10997162. Licensed CC0.

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