COSMIIC Supplement Request – MPS Module Development Abstract Summary We propose to develop a “multi-polar stimulation” (MPS) module that is designed for bipolar stimulation and stimulation of multi-polar nerve cuff electrodes. The MPS Module is an upgraded module based on the platform COSMIIC System stimulator module. Each MPS can drive any combination of four bipolar intramuscular and bipolar nerve cuff electrodes; or eight monopolar intramuscular electrodes. Compared to the PG4, the MPS has expanded stimulation channels (12 independent vs 4 monopolar) to accommodate additional electrode styles. Each contact has an independent current source and allows full current steering between each contact. The case of the MPS can also act as a return electrode, providing a total of 13 independent contacts. The MPS delivers a current-controlled, charge-balanced stimulus pulse that is capable of delivering stimulation for any style of muscle-based electrodes (maximum 20mA pulse amplitude) as well as the stimulation resolution necessary for nerve cuff-based electrodes (4μA resolution). The MPS includes impedance monitoring for each electrode. Impedance monitoring allows identification of a broken electrode or lead disconnection, and significantly enhances troubleshooting.