# T Cell Differentiation in Tissue Microenvironments

> **NIH NIH R13** · KEYSTONE SYMPOSIA · 2024 · $15,000

## Abstract

ABSTRACT
Support is requested for a Keystone Symposia conference entitled T Cell Differentiation in Tissue
Microenvironments, organized by Drs. Greg Delgoffe, Amanda Lund, Nikhil Joshi and Laura Mackay. The
conference will be held in Vancouver, British Columbia, Canada from February 2–6, 2025.
Normal and pathological immune responses function across tissues that harbor unique metabolic,
environmental, and cellular microenvironments. Therefore, the mechanisms that recruit and activate leukocytes,
define their interstitial function and survival, or promote their retention in particular tissues are crucial to
understanding how to boost, redirect, or restrict immune responses across the spectrum of health and disease.
While the topic of tissue specific immunity has been touched on in other meetings, this is the first conference to
integrate discussion across diverse tissues and disease contexts. The program will cover how various tissues
shape the immune responses that are generated within, while highlighting emerging technologies that are
enabling advancements in this field. The speaker lineup will attract a vast array of multidisciplinary scientists
thinking about T cell differentiation in tissues in the context of diverse diseases, such as cancer, autoimmunity,
and infection. In addition, as a joint meeting with the Keystone Symposia conference on Innate Immune Memory:
Mechanisms and Consequences, the intersections of audiences and researchers will enable dynamic crosstalk,
cross-disciplinary insights and collaboration towards understanding the interconnectedness of innate and
adaptive immunity, and interplay with tissue microenvironments.

## Key facts

- **NIH application ID:** 11000142
- **Project number:** 1R13AI186422-01
- **Recipient organization:** KEYSTONE SYMPOSIA
- **Principal Investigator:** TERRY L. SHEPPARD
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $15,000
- **Award type:** 1
- **Project period:** 2024-07-09 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11000142

## Citation

> US National Institutes of Health, RePORTER application 11000142, T Cell Differentiation in Tissue Microenvironments (1R13AI186422-01). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/11000142. Licensed CC0.

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