SUMMARY To provide a forum for immunologists (investigators and trainees) from the Upstate New York area and surrounding regions to present and discuss their research and build collaborations, the Upstate New York Immunology Conference was initiated in 1998 and initially included 53 participants from three institutions. This annual meeting has now grown to include ten institutions with an attendance of approximately 100 participants annually. The specific objectives of the meeting are: 1) to provide a forum for members of the regional immunology community to present their work, exchange ideas, and develop collaborations; 2) to give students and postdoctoral fellows an opportunity to meet distinguished national leaders in the field and other trainees and PIs from area institutions. 3) to allow students and postdoctoral fellows to present their work in a meeting format and obtain appropriate project feedback; 4) to increase local, national, and international awareness of immunology research being conducted in the region. The meeting also addresses career issues through workshops organized by the keynote speakers. The next meeting will be held October 21-24, 2024, at The Otesaga Resort Hotel, Cooperstown, NY. There will be two keynote speakers, four scientific symposia, two trainee poster sessions, and four oral poster presentation sessions. All those wishing to attend will be accommodated within The Otesaga Resort Hotel’s 300 rooms and extensive conference facilities.