The goal of the Society for Heart and Vascular Metabolism (SHVM) conference is to bring together scientists and trainees from around the globe to present and discuss cutting-edge research in the field of cardiac and vascular metabolism. This year’s meeting in St. Louis, Missouri, September 2024, will focus on the latest research regarding the role of interorgan crosstalk in the pathogenesis of cardiovascular disease (CVD). Most prevalent cardiovascular pathologies, such as heart failure and ischemia, have underlying metabolic derangements directly involved in disease progression, but recent studies have highlighted the relevance of interorgan crosstalk as a new frontier for cardiovascular research with the ultimate goal of ameliorating CVD. To that end, SHVM’s 2024 meeting is designed to foster ‘crosstalk’ between the investigative fields of heart and vascular metabolism and other key organ systems. Despite new investigations of interorgan communications, such as exosome trafficking as well as novel hormonal axes that affect the heart and vasculature, cross-disciplinary research has unique funding and operational barriers. This is not surprising given the significant challenges of creating multidisciplinary infrastructure and developing novel techniques evaluating heart and vascular metabolism in the context of manifold interorgan signals. Some scientists/trainees (PhD students, MD and postdoctoral fellows) may not feel equipped to tackle the unique barriers to performing cross-disciplinary research. To address these issues, this conference aims to provide a comprehensive and wide-ranging forum in which investigators from multiple disciplines will interact and discuss recent research studies that have resulted in meaningful outcomes relevant to cardiovascular metabolism. SHVM meetings have always featured strong participation of diverse trainees from many different regions in the United States and from around the globe. Moreover, SHVM has an established track record for fostering productive collaborations and career advancement. This year’s meeting will offer trainee workshops directed by top experts in metabolic imaging. Titled, “Cutting edge tools for the evaluation of myocardial metabolic metabolism and function,” the trainee workshop will facilitate interaction between trainees with junior and established investigators. The 2024 meeting will feature 2 keynote speakers, 19 plenary speakers, 4 speakers for Continuing Medical Education talks, 4 Early Investigator winner talks, and 9 other short talks selected from submitted abstracts, in addition to 2 workshops, and 2 poster sessions. The sessions will have strong representation from early-stage investigators, women, and underrepresented minorities. We are requesting funds to offset costs associated with trainee, speaker, and keynote speaker participation to continue the tradition of SHVM meetings, which are considered the premiere conferences in cardiac metabolism.