# Research Project-3: Effectiveness of an eHealth intervention for uptake of cervical cancer screening in Hispanic women

> **NIH NIH U54** · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · 2024 · $192,520

## Abstract

Project Summary
Research has highlighted the higher incidence and mortality rates of cervical cancer among Hispanic women
compared to non-Hispanic white women in the U.S. These disparities are even more pronounced when only
Hispanic immigrant women are considered because of greater individual and structural barriers to health care.
Effective community-based interventions are needed to address these health disparities, with the testing,
implementation, and evaluation of a promotora, or a lay health advisor, as one potentially effective strategy.
The overall objective of this study is to test an innovative, community-based, theory-driven, eHealth cervical
cancer screening intervention delivered in a group setting to Hispanic women living in northern Florida. The
primary research hypothesis is that a promotora intervention delivered electronically will increase adherence to
recommendations for cervical cancer screening among Hispanic women who are not up to date (≥3 years)
compared to women in a control group by over 15% favoring the intervention. The rationale that underlies the
proposed research is that interventions using promotoras are a culturally appropriate, potentially effective
strategy for increasing adherence to cervical cancer screening guidelines and follow-up for abnormal findings
in Hispanic populations. The three specific aims are to: (1) update a previously tested small media promotora
intervention (e.g., pamphlets and videos), which is designed to improve knowledge, attitudes, beliefs and
accurate risk perceptions for cervical cancer and human papillomavirus and promote positive cervical cancer
screening behaviors among Hispanic women; (2) test the effectiveness of the updated group-based, eHealth
promotora intervention using a cluster randomized controlled trial design to increase participation in cervical
cancer screening for Hispanic women who are not up to date with screening; and (3) conduct a cost-
effectiveness analysis of the promotora intervention. The study will be strengthened by the establishment of a
community-academic partnership. The contribution of the proposed research is expected to be the
development of an effective eHealth group intervention which can be delivered by a promotora to increase
screening among Hispanic immigrants in rural settings. Moreover, the intervention focuses on Hispanics who
have settled in the southeastern U.S., an understudied population in terms of cancer education research. At
the conclusion of the study, the following outcomes are expected: (1) refinement of a small media intervention
that is evidence-based; (2) improvement in diverse community partnership networks and opportunities for
building research infrastructure by working with the Community Engagement and Research Capacity cores;
and (3) identification of next steps for a follow-up study, including expanding the study to include HPV self-
sampling for cervical cancer screening.

## Key facts

- **NIH application ID:** 11001308
- **Project number:** 2U54MD007582-39
- **Recipient organization:** FLORIDA AGRICULTURAL AND MECHANICAL UNIV
- **Principal Investigator:** John S. Luque
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $192,520
- **Award type:** 2
- **Project period:** 1997-08-01 → 2029-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11001308

## Citation

> US National Institutes of Health, RePORTER application 11001308, Research Project-3: Effectiveness of an eHealth intervention for uptake of cervical cancer screening in Hispanic women (2U54MD007582-39). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/11001308. Licensed CC0.

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