ABSTRACT Through this proposal, we request funding to organize a symposium entitled "Engineered Vision Conference (EVC).” The main objective is to convene recognized global experts in basic and clinical vision research, cell and gene therapy, biomedical engineering, industry, as well as junior investigators, to discuss and advance the area of Engineered Vision (EV). This conference will specifically focus on three areas (1) bioelectronic devices, (2) cell-based therapies and (3) gene therapies. While these areas are distinct, they share some common engineering challenges such as in manufacturing as well as defining meaningful clinical endpoints. During the EVC, we aim to identify the challenges impeding the advancement of each of these three areas and formulate a strategic action plan to address these obstacles. We will specifically pinpoint areas of overlap that are relevant to two if not all three areas and try to develop a strategic plan to address these common challenges and opportunities. For instance, a technology like microelectromechanical systems might be applicable in all three areas, and the conference will explore how to effectively utilize such commonalities. Organizing a symposium aimed at advancing these three areas is highly relevant and timely. For example, the implementation of implantable and/or wearable bioengineered systems in the field of ophthalmology is highly significant, especially with the current emphasis on precision and personalized medicine, as well as the transformative power of deep learning artificial intelligence algorithms. Given the interdisciplinary nature of this conference, we have assembled researchers and clinicians with diverse expertise across these three domains to contribute to the overarching goal of Engineered Vision. Additionally, we will focus on diversity, equity and inclusion through a broad outreach plan. We will prioritize the training of junior faculty as well as students (trainees) through a robust poster and presentation program and an interactive conference format, which includes travel and best poster awards. Through symposium talks, sessions, and discussions, we will be able to explore the foundational aspects of EV while also identifying innovative approaches and state-of-the-art methodologies, accelerating significant breakthroughs and the development of groundbreaking therapeutics.