Project Summary/Abstract The proposed project relates to the development of an innovative, single-operator pneumothorax decompression device that aims to improve the safety and time efficiency of therapeutic decompression. The aim of neonatal pneumothorax decompression is to alleviate built-up air pockets inside the chest wall that threaten the functionality of vital organs. Current procedures require a medical provider to assemble a functional decompression “device” using multiple off-the-shelf modular components, which can be inefficient and time consuming in emergency situations. Two medical providers are generally required to achieve the therapy, which involves insertion of a needle into the chest wall with no feedback of needle depth. In addition, the needle is subject to movement, potentially harming surrounding lung tissue, as stability of the needle within the chest cavity is based solely on provider skill and steadiness. An innovative prototype device will be designed, manufactured and evaluated.