This SBIR research will demonstrate a superior method of respiratory monitoring that will be first to enable continuous predictive respiratory monitoring (CPRM) at the patient bedside and in the future at the pa*ent’s home. This research (phase 1 and 2) and innovative product research & development (phase 2) will enable commercialization of the Linshom CPRM that will move the entire field of respiratory monitoring from responsive (too late) to predictive, where patient respiratory decline is identified when health care providers can take action and pre-empt patient decline (i.e. rapid response activations, codes, ICU transfers). This will reduce morbidity, mortality and healthcare expense. The engineering research (phase 2) will re-design and miniaturize the sensor technology allowing these developments to be embedded in multiple additional, smaller form factors (i.e. nasal cannula, home use) to reach more patients in need of continuous, predictive respiratory monitoring.