# Interactive Gaming Platform to Facilitate Cognitive Interventions for Dementia

> **NIH NIH R43** · KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT · 2024 · $505,184

## Abstract

Abstract
Koronis Biomedical Technologies Corporation (KBT) proposes to develop and validate a novel cognitive
intervention to support informal caregivers and family of individuals living with MCI or AD/ADRD and
other cognitive impairments to preserve functional independence and reduce caregiver burden for in-
home care. As the number of older Americans has grown, so has the prevalence of aging-associated
diseases, including mild cognitive impairment (MCI), which may stabilize or progress to Alzheimer’s
disease (AD), the most prevalent dementia, and other related dementias (ADRD). The majority of
persons living with dementia live at home, where they receive the majority of their care from informal
caregivers and unpaid individuals such as family members, friends, and neighbors. Informal caregivers
provide services with enormous economic value, replacing or delaying institutionalization at significant
personal cost. Families and informal caregivers of persons living with MCI and AD/ADRD have an unmet
need for an affordable cognitive intervention that can help the care recipient preserve cognition, maintain
independence, and assist in their own care. The proposed research seeks to address this need by
building an in-home cognition training system that provides a modular series of short, easy-to-follow,
evidence-based cognitive training activities that slow the course of AD/ADRD, prevent the onset, and
reduce the burden. The system will employ a novel caregivers/care recipient training model that views
caregiver and family involvement as a critical component of the intervention process. In this model,
caregivers and family can cooperatively (and remotely) work to make the training activities person-
centered, monitor performance status, and increase positive interaction by emphasizing shared history
and the care recipients' preserved capabilities rather than their limitations. In Phase I, KBT will develop a
collaborative reminiscence therapy module, allowing caregivers to curate anecdotes and media (photos,
audio, video) to personalize the therapy. KBT will also prototype the caregiver portal and application
interfaces, which will be evaluated in a human usability assessment.

## Key facts

- **NIH application ID:** 11008556
- **Project number:** 1R43AG090220-01
- **Recipient organization:** KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT
- **Principal Investigator:** Timothy H. Riehle
- **Activity code:** R43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $505,184
- **Award type:** 1
- **Project period:** 2024-09-01 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11008556

## Citation

> US National Institutes of Health, RePORTER application 11008556, Interactive Gaming Platform to Facilitate Cognitive Interventions for Dementia (1R43AG090220-01). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/11008556. Licensed CC0.

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