# Portable Low-Cost Pulmonary Forced Oscillation Technique Device

> **NIH NIH SB1** · KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT · 2024 · $499,966

## Abstract

Project Summary Abstract
Koronis Biomedical Technologies and its collaborators propose to commercialize a low-cost, portable
respiratory assessment device using the forced oscillation technique (FOT). The proposed FOT
device requires zero skill from the subject and operator, making it ideal for occupational health
screening, physician office use, and home monitoring. The current gold standard for accurate and
repeatable measurement of lung function is spirometry. Spirometry is a pulmonary function test that
measures the volume and rate of airflow a patient can maximally exhale into a tube attached to a
precise airflow meter. The role of spirometers has been limited due to their reliance on technique
adherence. Unlike many medical diagnostic tests where the patient is essentially a passive
participant, spirometry requires active patient participation. The procedure requires the patient to take
the deepest breath possible and then exhale as hard as possible for as long as possible. The test is
normally repeated to ensure reproducibility. Spirometry results are highly dependent on patient
cooperation and effort. Patients often face a significant learning curve. Some patients cannot, or will
not, produce interpretable results. FOT measures pulmonary airway resistance and reactance. In
contrast to traditional spirometry, the key clinical advantage of FOT is that the technique is passive
and does not require the patient to breathe forcefully on command. In this project, all components of
the production system will be finalized and evaluated for usability and performance in human
evaluations along with market release under FDA market clearance.

## Key facts

- **NIH application ID:** 11010259
- **Project number:** 1SB1HL176360-01
- **Recipient organization:** KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT
- **Principal Investigator:** Patrick Lichter
- **Activity code:** SB1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $499,966
- **Award type:** 1
- **Project period:** 2024-09-01 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11010259

## Citation

> US National Institutes of Health, RePORTER application 11010259, Portable Low-Cost Pulmonary Forced Oscillation Technique Device (1SB1HL176360-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/11010259. Licensed CC0.

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