# Companion Animal and Animal Food Diagnostic Sample Analysis in Support of FDA Vet-LIRN Activities and Investigation.

> **NIH FDA U18** · UNIVERSITY OF PENNSYLVANIA · 2024 · $48,750

## Abstract

PROJECT SUMMARY
The Clinical Infec�ous Disease Laboratory at the Mathew J Ryan Veterinary Hospital (PA-Ryan), located at the
University of Pennsylvania School of Veterinary Medicine, currently oﬀers comprehensive microbiology,
parasitology and molecular biology veterinary diagnos�c services for companion animal and exo�c species. PA-
Ryan became a member of the Veterinary Laboratory Inves�ga�on and Response Network (VetLIRN) in 2017. It
also is aﬃliated with the PADLS on the New Bolton Center campus, which is a ﬁrst- �er laboratory member of
the Vet-LIRN. PA-Ryan is experienced in the analysis of a variety of sample and matrix types, including but not
limited to animal samples, environmental samples, water, and animal food products. PA-Ryan is accredited by
the American Animal Hospital Associa�on (AAHA) as a hospital-based laboratory. In addi�on to addressing the
current need for added laboratory capacity in the event of a large-scale outbreak or threat incident involving
companion animals or animal food, PA-Ryan will con�nue to further strengthen the Vet-LIRN through molecular
diagnos�c ac�vi�es that beter enable early detec�on of emerging pathogenic agents and facilitate the rapid
responses that can minimize harm and best protect both human and animal health. In the previous 5 years
(FY2018-FY2023), the PA-Ryan lab has had several successes as a VetLIRN laboratory including publica�on of 5
peer-reviewed ar�cle, 4 public presenta�ons, 2 public webpages and 1 standardized protocol. PA-Ryan has also
expanded its capacity for tes�ng by implementa�on of new technologies and standardized tests with other
VetLIRN laboratories. PA-Ryan has also par�cipated in numerous VetLIRN proﬁciency tests and interlaboratory
comparison exercises. PA-Ryan currently serves as a Source Lab for the VetLIRN AMR surveillance project and
has provided 756 isolates for Whole Genome Sequencing during the previous funding period. During the next
funding period, PA-Ryan will con�nue to partner with VetLIRN to standardize methods and quality procedures
along with faithfully conduct VPO directed case inves�ga�ons and other projects. PA-Ryan is dedicated to the
mission the VetLIRN sets forth “to improve veterinary medicine and promote public and animal health”.

## Key facts

- **NIH application ID:** 11018117
- **Project number:** 2U18FD006669-06
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Stephen Douglas Cole
- **Activity code:** U18 (R01, R21, SBIR, etc.)
- **Funding institute:** FDA
- **Fiscal year:** 2024
- **Award amount:** $48,750
- **Award type:** 2
- **Project period:** 2019-06-15 → 2029-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11018117

## Citation

> US National Institutes of Health, RePORTER application 11018117, Companion Animal and Animal Food Diagnostic Sample Analysis in Support of FDA Vet-LIRN Activities and Investigation. (2U18FD006669-06). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/11018117. Licensed CC0.

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