# Concentration Determination of Tulathromycin Residues (CP-60,300) in Liver and Injection Site Tissues of Goats Receiving One Subcutaneous Injection of DRAXXIN 25 (25 mg/mL) at 2.5 mg/kg Bodyweight

> **NIH FDA R01** · IOWA STATE UNIVERSITY · 2024 · $250,000

## Abstract

PROJECT SUMMARY
This project aims to address the significant problem of bacterial pneumonia in goats, which is a
major cause of morbidity and mortality and represents a significant welfare challenge for
operations in the United States. Currently, there is only one FDA-approved antibiotic for the
treatment of respiratory disease in goats, which requires daily administration. That decreases
efficacy in situations where owner compliance with labeled instructions is lacking. To address
this problem, the proposed research aims to determine an appropriate withdrawal period
following administration of Draxxin® 25 in goats except breeding and lactating goats. The
expected outcome is to have quantified data from incurred liver and injection site tissues that
can be utilized to determine a meat withdrawal period. Following completion of this work, we will
have completed all the work associated with all the necessary technical sections which we be
able to submit to FDA CVM for consideration for a label approval. The label approval of
Draxxin® 25 will make it easier for veterinarians to use tulathromycin in goats with confidence in
scientifically based labeled slaughter withdrawal times.

## Key facts

- **NIH application ID:** 11022650
- **Project number:** 1R01FD008252-01
- **Recipient organization:** IOWA STATE UNIVERSITY
- **Principal Investigator:** Patrick J Gorden
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** FDA
- **Fiscal year:** 2024
- **Award amount:** $250,000
- **Award type:** 1
- **Project period:** 2024-09-01 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11022650

## Citation

> US National Institutes of Health, RePORTER application 11022650, Concentration Determination of Tulathromycin Residues (CP-60,300) in Liver and Injection Site Tissues of Goats Receiving One Subcutaneous Injection of DRAXXIN 25 (25 mg/mL) at 2.5 mg/kg Bodyweight (1R01FD008252-01). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/11022650. Licensed CC0.

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