# Near-infrared Fluorescent Probes for Sensitive Detection of NADH in Live Cells

> **NIH NIH R15** · MICHIGAN TECHNOLOGICAL UNIVERSITY · 2024 · $100,000

## Abstract

Our proposal endeavors to secure the Shimadzu LCMS-2050 system, aiming to propel our
research in fluorescent probe synthesis for biomedical applications to new heights. This cutting-
edge instrument is poised to redefine our approach by offering real-time monitoring capabilities,
enabling the exploration of innovative reaction conditions, optimization of synthetic methods,
and rapid identification of lead candidates. The system's technical excellence lies in significantly
enhanced efficiency, streamlined processes, and reduced resource consumption. Beyond its
technical merits, this proposal underscores our commitment to spearheading impactful and
resource-efficient scientific innovation in our field. By investing in state-of-the-art technology and
adopting sustainable, responsible resource management practices, we are dedicated to advancing
our research at the forefront of the discipline. The strategic acquisition of this advanced
instrumentation positions our research group to pioneer groundbreaking fluorescent probes
using more efficient and eco-friendly synthetic methodologies.

## Key facts

- **NIH application ID:** 11034558
- **Project number:** 3R15GM146206-01S2
- **Recipient organization:** MICHIGAN TECHNOLOGICAL UNIVERSITY
- **Principal Investigator:** Haiying Liu
- **Activity code:** R15 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $100,000
- **Award type:** 3
- **Project period:** 2022-06-01 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11034558

## Citation

> US National Institutes of Health, RePORTER application 11034558, Near-infrared Fluorescent Probes for Sensitive Detection of NADH in Live Cells (3R15GM146206-01S2). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/11034558. Licensed CC0.

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