PROJECT SUMMARY The parent project of this administrative supplement application is the NIAID U19-funded Maternal Immunization and Determinants of Infant Immunity (MADI) program. MADI is a multidisciplinary investigation of immunity during pregnancy and the factors linking maternal immune status to child health. MADI has brought together diverse investigators with powerful human subjects cohorts contributing rich clinical, sociodemographic, and high-throughput data sets. The MADI Data Management and Biostatistics Core has designed, built and implemented a custom data management platform to support MADI’s immunological research. This robust and flexible platform was developed in accordance with FAIR data management principles that supports MADI with FAIR data management practices. Our goals for this administrative supplement funding are to further develop this tool to include automated data sharing functions; to develop MADI data sets as a data asset compatible with the NIAID Data Ecosystem; and to develop the platform as an open-source containerized software that can be freely shared with investigators in the wider community in support of their data management and sharing needs.