# National Resource for Advanced NMR Technology

> **NIH NIH RM1** · FLORIDA STATE UNIVERSITY · 2024 · $141,821

## Abstract

A major part of the scien�fic program of the parent project (1RM1GM148766) is based on the world’s
highest field high resolu�on NMR magnet, the 36 T series connected hybrid (SCH). This instrument is
opening new fron�ers in the studies of a wide array of biological systems, chemical compounds, and
advanced materials. A groundbreaking field regula�on system was developed and implemented for the
SCH which suppresses field fluctua�ons down to 0.3 ppm and has enabled a variety of NMR experiments
– as proven by the extensive publica�on record in the last five years. We are ready to take the next step
and enable the SCH to make unmatched measurements of spin-1/2 nuclides in biological systems. This
will require speeding up the control loop of the field regula�on system from a rate of 40 Hz to a rate of
about 1 kHz. Extensive preliminary tes�ng on our current system has demonstrated the improvement
possible with a faster control loop. To accomplish this increase in speed, we propose to replace our ca.
2013 Na�onal Instruments electronics with the much more powerful 2024 version. The new hardware
has the increased FPGA fabric and backplane data transfer capability to make the faster control loop
possible. It also runs a currently supported development environment and will be compliant with ever
increasing LAN and internet security requirements. The field regula�on technology developed with the
new system may find applica�on in regula�ng nonpersistent NMR magnets based on high temperature
superconductors.

## Key facts

- **NIH application ID:** 11037202
- **Project number:** 3RM1GM148766-02S1
- **Recipient organization:** FLORIDA STATE UNIVERSITY
- **Principal Investigator:** William W Brey
- **Activity code:** RM1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $141,821
- **Award type:** 3
- **Project period:** 2023-04-01 → 2028-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11037202

## Citation

> US National Institutes of Health, RePORTER application 11037202, National Resource for Advanced NMR Technology (3RM1GM148766-02S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/11037202. Licensed CC0.

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