# A Chemo-Mimetic Platform to Reprogram Metalloenzymes for Non-Natural Biocatalytic C-H Functionalization Reactions

> **NIH NIH R35** · JOHNS HOPKINS UNIVERSITY · 2024 · $238,198

## Abstract

Project summary. This proposal is for the acquisition of an Agilent Ultivo Triple Quadrupole LC/MS
System for high-throughput multiplex enantiomeric screening, aimed at developing new biocatalysts for
enantioselective non-natural transformations. The application entails justifications for this purchase and
delineates how this new instrument would facilitate our R35 research, improve the productivity of my
laboratory, and expand the new research horizons of our work. It also provides justification for the need of
this instrument as well as justification for the price of the instrument being purchased.

## Key facts

- **NIH application ID:** 11037339
- **Project number:** 3R35GM147639-02S1
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** Xiongyi Huang
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $238,198
- **Award type:** 3
- **Project period:** 2022-08-01 → 2027-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11037339

## Citation

> US National Institutes of Health, RePORTER application 11037339, A Chemo-Mimetic Platform to Reprogram Metalloenzymes for Non-Natural Biocatalytic C-H Functionalization Reactions (3R35GM147639-02S1). Retrieved via AI Analytics 2026-06-11 from https://api.ai-analytics.org/grant/nih/11037339. Licensed CC0.

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