# BIOLOGICAL TESTING FACILITY - CONTRACEPTIVE TARGET DATABASE AND APPLICATION

> **NIH NIH N01** · SRI INTERNATIONAL · 2024 · $178,024

## Abstract

Early phase non-steroidal contraceptive discovery and development is limited by known targets
and readily accessibility of this information. It is important to facilitate the discovery, curation
and availability of contraceptive targets with the aim of developing new approaches to advance
next generation of safe contraceptive drug/device. To alleviate this obstacle, bioinformatics driven
approach to identify and curate those targets from the existing databases was established. To
further allow easy accessibility and friendly user interface for this database, a web application is
needed. The Biological Testing Facility has bioinformatics and web design and application
capability to achieve this task, in addition to permit rapid evaluation (in vitro and in vivo) of new
compositions of matter to the target, efficacy evaluation, safety/ toxicology assessment, drug
formulations, delivery systems, and devices for contraceptives followed by clinical batch
preparation/ release and continued stability testing of drugs to be evaluated in clinical trials. The
BTF provides overall project management and the capabilities to support all phases of novel target
product identification, drug discovery/ optimization, preclinical activities and development of
contraceptives and associated tasks leading to the filing of investigational new drug (IND)
applications.

## Key facts

- **NIH application ID:** 11042002
- **Project number:** 75N94020D00003-P00002-759402200001-1
- **Recipient organization:** SRI INTERNATIONAL
- **Principal Investigator:** DEBORAH BUNIN
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $178,024
- **Award type:** —
- **Project period:** 2023-11-17 → 2024-11-16

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11042002

## Citation

> US National Institutes of Health, RePORTER application 11042002, BIOLOGICAL TESTING FACILITY - CONTRACEPTIVE TARGET DATABASE AND APPLICATION (75N94020D00003-P00002-759402200001-1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/11042002. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*