# COBRE in Stroke Recovery Administrative Supplement - Team Science

> **NIH NIH P20** · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2024 · $990,225

## Abstract

TEAM SCIENCE – PROJECT SUMMARY
The ultimate purpose of the COBRE in Stroke Recovery is to improve the recovery of those who have suffered
a stroke such that long-term quality of life is improved. Our primary focus is on developing and testing
mechanism-based interventions to rehabilitate individuals with post-acute or chronic impairments and
disabilities. We seek to accomplish this through the following Overall specific aims: 1) Expand our critical mass
of funded investigators; 2) Strengthen innovative scientific cores that advance stroke recovery research; and 3)
Advance the ongoing development of an independent, sustainable, multidisciplinary thematic research program.
Our COBRE has been developing the skills and infrastructure to address the unique healthcare needs of the
state of South Carolina (SC). Specifically, SC is in the “buckle” of the stroke belt, having one of the highest
incidences of stroke and age-adjusted stroke mortality in the nation.1 Further, it has the 14th largest rural
population2 in the nation, and all 46 SC counties qualify in whole or in part as Health Resources & Services
Administration (HRSA)-designated Medically Underserved Communities. Thus, there is an overarching need to
develop tele-interventions to serve rural communities with limited access to stroke rehabilitation care. Our
COBRE has focused on developing innovative tools, methods, and interventions to address the burden of post-
stroke disability. Additionally, through innovative approaches in psychosocial functioning and novel device
development, our team is invested in ensuring that rehabilitation gains that occur in the clinic translate into lasting
gains in an individual’s lived environment. Our interdisciplinary Team Science project brings together engineers,
occupational therapists, neuropsychologists, cognitive psychologists, neuroscientists, and data scientists.
The research question to be addressed by this COBRE Team Science Supplement is “Can an interdisciplinary
team science research approach successfully improve upper extremity (UE) stroke recovery, especially for rural
populations, by translating innovative interventions to the home setting?” Specifically, our interdisciplinary team
science research project comprises three innovative, synergistic co-projects that use tele-interventions for UE
stroke rehabilitation and test three different ways to improve rehabilitation outcomes in the home. 1) The Seo
Co-Project aims to improve the adherence to and performance of home-based UE stroke recovery interventions.
The project will objectively track and measure the quantity and quality of rehabilitation exercise and use a sensor-
based stepped-care behavioral intervention that monitors adherence, administers ecological momentary
assessments to obtain a reason for non-adherence, and provides relevant resources. 2) The Aghamoosa Co-
Project aims to address the multisystem functional deficits that result from stroke and may pose barriers to UE
recovery. The...

## Key facts

- **NIH application ID:** 11046888
- **Project number:** 3P20GM109040-10S2
- **Recipient organization:** MEDICAL UNIVERSITY OF SOUTH CAROLINA
- **Principal Investigator:** STEVEN A. KAUTZ
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $990,225
- **Award type:** 3
- **Project period:** 2014-06-02 → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11046888

## Citation

> US National Institutes of Health, RePORTER application 11046888, COBRE in Stroke Recovery Administrative Supplement - Team Science (3P20GM109040-10S2). Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/grant/nih/11046888. Licensed CC0.

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