SUMMARY The Center for Viral Systems Biology (CViSB) proposes to host the 2024 Annual Meeting of the Systems Biology for Infectious Diseases Consortium on September 25th and 26th in San Diego, California. The National Institutes of Health (NIH) U19 funding mechanism provides substantial scientific or program staff assistance, guidance, coordination, and participation in project activities. This includes facilitating collaborations and leveraging resources available to the Program. The annual Systems Biology meeting exemplifies these goals by fostering collaboration among Centers and maximizing consortium resources. However, the primary focus of annual meetings remains reporting research progress, identifying new research directions, and updating NIAID on critical needs. As the host of the 2024 annual meeting, CViSB will organize the two-day event to (1) encourage participation by Systems Biology in Infectious Diseases Research Center members, NIAID Program staff, and Scientific Advisory Group members, (2) showcase Center research, (3) provide professional development opportunities and (4) promote discussion and collaboration.