Functionally guided adult whole brain cell atlas in human and NHP

NIH RePORTER · NIH · UM1 · $85,677 · view on reporter.nih.gov ↗

Abstract

Project Abstract Integral to all aims of the parent grant (from here on, Human Mammalian Brain Atlas, or HMBA) is a hospice/palliative care brain donor program which will collect functional imaging data from participants antemortem to integrate with the whole brain atlas generated postmortem. There are, however, disparities in access to palliative and hospice care, with people from minoritized racial and ethnic backgrounds less able to access these forms of care. These disparities have the potential to disrupt HMBA’s ability to meaningfully include and positively impact people from minoritized groups. This supplement will support post-baccalaureate researcher Zoë Hale as they assist in designing and facilitating a series of qualitative interviews with hospice and palliative care workers working within underrepresented minority groups. This supplement will have two complementary, primary aims: (1) conduct a comprehensive literature review encompassing ethical, moral, and societal impact of creating a whole brain atlas on minoritized groups; (2) conduct a qualitative interview project to engage with the views of hospice and palliative care workers in minoritized groups on the ethical and moral issues related to brain atlasing. These complementary aims will provide HMBA’s hospice/palliative care brain donor program on best practices for interacting with and meaningfully including individuals from minoritized communities. This project serves to train and guide Zoë Hale toward a robust career of NIH-supported research at the intersection of the brain sciences and bioethics. Her plan includes collaboration with professionals across both the humanities and sciences to enhance her humanist and qualitative research abilities.

Key facts

NIH application ID
11061701
Project number
3UM1MH130981-03S3
Recipient
ALLEN INSTITUTE
Principal Investigator
Ed Lein
Activity code
UM1
Funding institute
NIH
Fiscal year
2024
Award amount
$85,677
Award type
3
Project period
2022-08-22 → 2025-04-24