# Examining the effect of biological sex on the tumor microenvironment and immunotherapy response

> **NIH NIH U01** · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $42,363

## Abstract

Project Summary
The parent grant focuses on the genetic determinants of distinct immune
microenvironments and response to immunotherapy. The objective focuses on determining
the genes regulating tumor composition in order to enhance tumor immunity. Similarly, this
project focuses on determining the tumor microenvironment composition between males
and females before immunotherapy a critical cofactor in all our genetic analyses.

## Key facts

- **NIH application ID:** 11062035
- **Project number:** 3U01CA282114-02S1
- **Recipient organization:** ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- **Principal Investigator:** Brian D Brown
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $42,363
- **Award type:** 3
- **Project period:** 2023-09-19 → 2028-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11062035

## Citation

> US National Institutes of Health, RePORTER application 11062035, Examining the effect of biological sex on the tumor microenvironment and immunotherapy response (3U01CA282114-02S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/11062035. Licensed CC0.

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