# HIPC Data Coordinating Center

> **NIH NIH U01** · LA JOLLA INSTITUTE FOR IMMUNOLOGY · 2024 · $469,233

## Abstract

Supplement PROJECT SUMMARY/ABSTRACT
The proposed work in this project will be a continuation of the duties previously performed for the IMPACC
project. This includes preparing both the computable processed data and the raw data files for the main
IMPACC study assays and type 1 papers for repository deposition, submitting the data to appropriate
repositories, mainly ImmPort and dbGaP, and interfacing with repository curators.
Parent Award PROJECT SUMMARY/ABSTRACT
The Human Immunology Project Consortium (HIPC) was founded in 2010 to create a network of independent
centers focused on measuring human immune responses with high-throughput systems immunology
approaches coupled with detailed clinical phenotyping. We propose to develop a HIPC Coordinating Center
(HCC) that will provide data more rapidly and effectively to the broader scientific community, and also serve
the entire HIPC by increasing the value of the research performed at HIPC Centers. In parallel, the HCC will
serve as a promoter of cross-HIPC collaborations through the organization of multi-center analysis projects
and a centralized Portal to provide a space for the exchange of ideas. Specifically, the HCC will continue the
development of shared data standards, provide a central Knowledgebase of study results, establish tools to
visualize and analyze data, lead synergistic cross-center analysis efforts, provide a Portal to make the tools
and data broadly accessible, and provide administrative support for the activities of HIPC subcommittees and
management of the Infrastructure and Opportunity Fund (IOF) program. Our team has proven experience in
running programs of similar scale and complexity. We also have the necessary familiarity with the HIPC
network, with our team including current PIs of the Data Standards IOF project, the Signatures IOF project,
clinical information capture, and the existing ImmuneSpace data portal. This proposal leverages this combined
experience and infrastructure while, in parallel, implementing various significant and necessary improvements
facilitated by the tighter integration and the 5-year time horizon of this dedicated HCC grant.

## Key facts

- **NIH application ID:** 11063738
- **Project number:** 3U01AI167892-03S2
- **Recipient organization:** LA JOLLA INSTITUTE FOR IMMUNOLOGY
- **Principal Investigator:** Steven H. Kleinstein
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $469,233
- **Award type:** 3
- **Project period:** 2024-05-16 → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/11063738

## Citation

> US National Institutes of Health, RePORTER application 11063738, HIPC Data Coordinating Center (3U01AI167892-03S2). Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/grant/nih/11063738. Licensed CC0.

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