Title: Enhancing Data Science Capacity at Northeastern Illinois University Summary of the data science supplement for Northeastern Illinois University (NEIU), MSI partner of the U54 ChicagoCHEC Chicago's systemically underserved communities have disproportionately high cancer rates. The Chicago Cancer Health Equity Collaborative (ChicagoCHEC) is a comprehensive partnership between the two federally designated Hispanic Serving Institutions, the University of Illinois at Chicago (UIC) and Northeastern Illinois University (NEIU), and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University (NU-LCC). Dedicated to advancing cancer health equity through rigorous and innovative science, education, and engagement of Chicago's underserved communities, ChicagoCHEC relies on a nurturing hub of four Cores (Administrative, Planning and Evaluation, Research Education, and Outreach) and a research project funding program. This data science supplement has a primary focus on developing research, educational, and outreach activities to increase the capacity in data science at NEIU, the research-active, Minority Serving Institution (MSI) partner of the ChicagoCHEC initiative. The proposed research activities in this supplement application complement and enhance the overall ChicagoCHEC partnership goals. The education activities are centered around development of new and adapting existing courses in data sciences for undergraduate and graduate students at NEIU. Outreach activities focus on expanding partnerships with underserved communities, specifically Chicago Public Schools in the immediate vicinity of NEIU, and developing education programs using culturally appropriate education tools about the importance of data science and its benefits. As part of the ChicagoCHEC partnership, the goals of this data science supplement application are centered within NEIU to build research capacity, strengthen and expand NEIU's partnerships and develop new curriculum by training our faculty adopt the data science initiative in their research and courses within the framework of cancer disparities. We intend to achieve these objectives through three main aims including establishing partnership with Metropolitan Chicago Data-science Corps (MCDC) and organizing an informative workshop for NEIU faculty to learn and expand on their expertise in data science resources and tools available to incorporate in courses and their own research. ChicagoCHEC will leverage the momentum forged by this data science supplement to drive innovative cancer research, research education, and community outreach and engagement that cuts across disciplinary and institutional boundaries.